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Proposal for a modified T-classification for oral cancer. The DOSAK
1Department of Maxillo-facial Surgery, University Medical School, DOSAK Central Tumour Registry/Frankfurt am Main, Germany.
Summary
The Union for International Cancer Control (UICC) is modifying the TNM staging system for oral cavity and oropharynx cancers. Adding tumor thickness to the T category improves the system's prognostic accuracy for squamous cell carcinomas.
Area of Science:
- Oncology
- Cancer Staging
- Head and Neck Cancers
Background:
- The Union for International Cancer Control (UICC) is updating the TNM staging system.
- Accurate cancer staging is crucial for treatment planning and prognosis.
- Existing TNM classifications require refinement for specific cancer types.
Purpose of the Study:
- To propose a modification to the T category of the TNM system for oral cavity and oropharynx squamous cell carcinomas.
- To enhance the prognostic relevance of the TNM classification.
- To incorporate tumor thickness as a key factor in T staging.
Main Methods:
- Utilizing data from the DOSAK tumor registry, encompassing over 3000 cases.
- Analyzing primary squamous cell carcinomas of the oral cavity and oropharynx.
- Developing a proposal for a new T category based on tumor characteristics.
Main Results:
- A revised T category proposal has been calculated using a large dataset.
- Tumor thickness was identified as a significant prognostic factor.
- The proposed modification aims to improve staging accuracy.
Conclusions:
- The integration of tumor thickness into the T component of the TNM system enhances its prognostic value.
- This modification is expected to improve the classification of oral cavity and oropharynx cancers.
- The proposed changes will be considered for the upcoming UICC TNM system publication.