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Related Experiment Videos

MRI of extraskeletal osteosarcoma

D G Varma1, A G Ayala, S Q Guo

  • 1Department of Diagnostic Radiology, University of Texas M. D. Anderson Cancer Center, Houston 77030.

Journal of Computer Assisted Tomography
|May 1, 1993
PubMed
Summary

Extraskeletal osteosarcoma of the thigh is rare and may not show calcifications on MRI. Imaging findings can be non-specific, but this diagnosis should be considered for thigh soft-tissue masses.

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Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Extraskeletal osteosarcoma is a rare malignant neoplasm.
  • Diagnosis can be challenging due to non-specific imaging features.

Purpose of the Study:

  • To illustrate the magnetic resonance imaging (MRI) findings of extraskeletal osteosarcoma of the thigh.
  • To correlate imaging findings with pathological examination in four cases.

Main Methods:

  • Retrospective review of four cases of extraskeletal osteosarcoma of the thigh.
  • Analysis of MRI findings, including T1-weighted and T2-weighted imaging, with and without contrast administration.
  • Radiologic-pathologic correlation.

Main Results:

  • Calcifications or osteoid material were not visible on MRI or conventional radiography in any of the four tumors.

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  • Three tumors appeared well-demarcated on MRI, correlating with pseudoencapsulation.
  • These three tumors showed heterogeneous appearance, hyperintensity to muscle on T1-weighted imaging, and high signal intensity on T2-weighted imaging.
  • The fourth tumor exhibited cystic, hemorrhagic, and solid components on MRI, confirmed by pathology.

    • Conclusions:

    • MRI findings in extraskeletal osteosarcoma are non-specific.
    • Extraskeletal osteosarcoma should be included in the differential diagnosis of thigh soft-tissue masses, especially in the appropriate age group, even without detectable calcifications.