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Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
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[Allergic bronchopulmonary aspergillosis (allergic bronchopulmonary fungal diseases)]

T Kino1

  • 1Department of Internal Medicine, Kobe Teishin Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|March 1, 1993
PubMed

Insights

Allergic bronchopulmonary aspergillosis (ABPA) is an allergic lung disease caused by Aspergillus fungus. Diagnosis involves recurrent symptoms, lung abnormalities, high IgE, and eosinophilia, with a call to revisit original diagnostic criteria.

Area of Science:

  • Pulmonology
  • Allergology
  • Mycology

Background:

  • Allergic bronchopulmonary aspergillosis (ABPA) is an allergic disease.
  • It is caused by viable Aspergillus fungus in the bronchi.
  • Type I and type III hypersensitivity reactions to the fungus are involved.

Purpose of the Study:

  • To define Allergic Bronchopulmonary Fungal Diseases (ABPF) as a broader category.
  • To emphasize the importance of Aspergillus in ABPA.
  • To advocate for a return to the original diagnostic criteria.

Main Methods:

  • Clinical findings: recurrent fevers, cough, mucopurulent sputum with eosinophils and fungus.
  • Radiological evidence: recurrent lung collapse and consolidation.
  • Laboratory findings: blood eosinophilia and elevated serum IgE.

Main Results:

  • ABPA presents with characteristic clinical, radiological, and serological findings.
  • Other fungi can cause similar allergic diseases, termed ABPF.
  • Existing diagnostic criteria vary, suggesting a need for standardization.

Conclusions:

  • ABPA is a distinct allergic pulmonary disease.
  • The term ABPF encompasses similar conditions caused by other fungi.
  • Revisiting the 1952 report by Hinson et al. is recommended for diagnostic clarity.

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