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[Autonomic diabetic neuropathy]

P Valensi1

  • 1Service d'Endocrinologie, Diabétologie, Nutrition, Hôpital Jean-Verdier, Bondy.

Presse Medicale (Paris, France : 1983)
|February 6, 1993
PubMed
Summary
This summary is machine-generated.

Diabetic autonomic neuropathy is common and often asymptomatic. Cardiac autonomic neuropathy, even when subclinical, indicates a poor prognosis, necessitating further research into effective treatments.

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Area of Science:

  • Neurology
  • Endocrinology
  • Cardiology

Context:

  • Diabetic autonomic neuropathy (DAN) is frequently subclinical, presenting diverse symptoms affecting gastrointestinal, urinary, genital, cardiac, sudoral, vasomotor, and pupillary functions.
  • Standardized cardiovascular tests offer feasible and reproducible methods for assessing parasympathetic and sympathetic nervous system control in diabetic patients.

Purpose:

  • To investigate the prevalence and diagnostic utility of cardiovascular tests in evaluating diabetic autonomic neuropathy.
  • To determine the prognostic significance of cardiac autonomic neuropathy in the diabetic population.

Summary:

  • Diabetic autonomic neuropathy is often asymptomatic but detectable through cardiovascular tests assessing autonomic function.
  • These tests reveal that cardiac autonomic neuropathy, even in its subclinical stages, is associated with a poor prognosis.

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  • Current treatments primarily focus on symptom management, with optimized glycemic control and aldose reductase inhibitors being potential therapeutic strategies, though long-term efficacy requires further validation.

    • Impact:

    • Highlights the prognostic importance of subclinical cardiac autonomic neuropathy in diabetes.
    • Emphasizes the role of cardiovascular autonomic function tests in routine diabetic care.
    • Identifies areas for future research in the long-term effectiveness of DAN treatments.