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[Normal and induced Hg release from different amalgams]
M Zimmermann1, R Mairgünther, T Scheuber
1Klinik und Poliklinik für Kieferchirurgie, Universität München.
Summary
Dental amalgams containing gamma-2 caused higher mercury (Hg) levels in urine compared to gamma-2-free versions. Dimaval enhanced mercury elimination, but levels remained safe. Gamma-2-free amalgams are recommended.
Area of Science:
- Dental materials science
- Toxicology
- Environmental health
Background:
- Dental amalgam is a widely used restorative material.
- Concerns exist regarding mercury release from dental amalgams.
- The presence of gamma-2 phase in amalgam composition may influence mercury release.
Purpose of the Study:
- To compare mercury load from gamma-2 containing and gamma-2 free dental amalgams.
- To assess the effect of Dimaval on mercury elimination after amalgam exposure.
- To evaluate the toxicological relevance of mercury exposure from dental amalgams.
Main Methods:
- Experimental investigation with 20 subjects without prior amalgam fillings.
- Standardized application of artificial amalgam surfaces (gamma-2 containing and gamma-2 free).
- Measurement of mercury concentrations in 24-hour urine samples before and after challenge with Dimaval.
Main Results:
- Amalgam containing gamma-2 significantly increased mercury concentrations in urine.
- Dimaval administration intensified mercury elimination rate.
- All measured mercury levels remained below toxicologically relevant concentrations.
Conclusions:
- Gamma-2 containing dental amalgams contribute to increased mercury load.
- Use of gamma-2 free amalgams is advisable to minimize heavy metal exposure.
- Development of improved dental materials and enhanced caries prevention are crucial.