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Updated: Jul 9, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
Factor V inhibitor in thrombosis
A Kapur1, P R Kelsey, P E Isaacs
1Department of Medicine, Victoria Hospital, Blackpool, Lancashire, United Kingdom.
Abstract:
A 68-year-old previously well woman developed sudden onset of limb gangrene in association with liver dysfunction. An immediately acting inhibitor to factor V with some of the features of lupus anticoagulant was demonstrated. The patient required limb amputation within 2 weeks and activity of the anticoagulant seemed to be on the decline 6 months later.
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