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Updated: Aug 4, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
A new method to assess contact lens care compliance
F D Turner1, J M Stein, D P Sager
1Alcon Laboratories, Inc., Fort Worth, TX 76115.
Abstract:
Failure to comply with contact lens care instructions is a conspicuous finding among both symptomatic and asymptomatic patients. We used a new methodology to quantify the extent of noncompliance and its clinical significance among 170 soft lens wearers. All patients were interviewed and asked to demonstrate their lens care practices. The significance of deviations from package insert instructions was assessed by 22 ophthalmologists and optometrists with regard to potential impact on safety and comfort. Virtually all patients were noncompliant with at least one required procedure. Noncompliant behavior that could significantly affect safety was more common and judged by practitioners to be of more concern than deviations that could affect comfort. Fifty-seven percent of the patients used disinfection procedures that could seriously affect safety. Overall, the study methodology was found to be very effective both for quantifying noncompliance and for evaluating its clinical significance.

