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Pathophysiology of dermatophyte infections
1Department of Dermatology, University of California-San Francisco.
Journal of the American Academy of Dermatology
|May 1, 1993
Summary
Dermatophyte infections, though common, are often persistent and recurring. This overview covers common types like tinea pedis and onychomycosis, including complex cases.
Area of Science:
- Dermatology
- Mycology
- Infectious Diseases
Background:
- Dermatophyte infections represent a significant and common clinical challenge.
- These fungal infections are frequently refractory and recurrent, despite often being perceived as minor ailments.
Purpose of the Study:
- To provide a comprehensive overview of prevalent dermatophyte infections.
- To discuss causes, symptoms, differential diagnosis, and clinical course.
- To address complicated scenarios including immunocompromised patients and zoologically acquired infections.
Main Methods:
- Literature review and synthesis of current knowledge on dermatophytoses.
- Focus on prevalent clinical presentations: tinea pedis, tinea cruris, tinea capitis, tinea corporis, and onychomycosis.
- Inclusion of discussions on challenging cases and specific patient populations.
Main Results:
- Detailed descriptions of the clinical features and management of common dermatophyte infections.
- Identification of factors contributing to treatment refractoriness and recurrence.
- Exploration of atypical presentations and specialized patient groups.
Conclusions:
- Dermatophyte infections require thorough understanding and management due to their potential for chronicity.
- Accurate diagnosis and consideration of complicating factors are crucial for effective treatment.
- Further research into novel therapeutic strategies may be warranted for refractory cases.