Jove
Visualize
Contact Us

Related Experiment Videos

A microbiologic study of diluted sclerotherapy solutions

N S Sadick1, B Farber

  • 1Division of Dermatology, Cornell University Medical College, New York, New York.

The Journal of Dermatologic Surgery and Oncology
|May 1, 1993
PubMed
Summary

Diluting sclerosing agents for sclerotherapy using aseptic techniques maintains sterility for at least three months. This finding supports safe practices in vascular treatments and reduces infection risks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of healthcare costs for patients with pemphigus and bullous pemphigoid in an academic centre in Germany.

The British journal of dermatology·2019
Same author

Skin cancer concerns particular to women.

International journal of women's dermatology·2017
Same author

Skin cancer concerns particular to women.

International journal of women's dermatology·2017
Same author

Novel method for facial rejuvenation using Er:YAG laser equipped with a spatially modulated ablation module: An open prospective uncontrolled cohort study.

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology·2016
Same author

Quasi-life self-organizing systems: based on ensembles of succinylated derivatives of interferon-gamma.

Current medicinal chemistry·2011
Same author

Isolation of Mycobacterium bolletii from human omentum after laparoscopic gastric banding.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2010
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Vascular medicine
  • Microbiology
  • Pharmaceutical science

Background:

  • Sclerotherapy involves diluting agents to achieve effective vessel closure.
  • Minimal sclerosant concentration (MSC) is crucial for optimal outcomes.
  • Microbial contamination of infusates can lead to serious infections.

Purpose of the Study:

  • To assess the microbial content of diluted sclerosing agents.
  • To determine the sterility of common sclerotherapy agents at various concentrations.
  • To evaluate the impact of dilution on the microbial stability of sclerosing solutions.

Main Methods:

  • Prepared dilutions of hypertonic saline, Polidocanol, sodium tetradecyl sulfate, and polyiodide iodide.
  • Sterile conditions were maintained throughout the dilution process.
  • Analyzed microbial (bacterial, fungal, spore) content over 3 months using standardized utilization indices.

Main Results:

  • All tested sclerosing agent dilutions remained sterile for bacteria and fungi.
  • Sterility was maintained across all tested concentrations and time intervals.
  • No microbial growth was observed in any of the cultures.

Conclusions:

  • Appropriate aseptic techniques ensure the sterility of diluted sclerosing solutions.
  • Diluted sclerosing agents can remain sterile for at least 3 months under simulated daily use.
  • This supports the safe practice of preparing customized sclerotherapy agent concentrations.

Related Experiment Videos