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Updated: Aug 10, 2026

Assessing Whole-Body Lipid-Handling Capacity in Mice
Published on: November 24, 2020
[Changes in the phospholipid and cholesterol content of rat tissues during adaptation to high altitude at different
Abstract:
Studies have been made on the contents of total lipids, cholesterol, phospholipids and the level of lipid peroxidation in rats adapted to a high altitude (3.200 m for 30 days) at temperatures 10 and 30 degrees C. It was shown that at lower temperature, high altitude adaptation is paralleled by more significant activation of lipid peroxidation, the decrease of phosphatidylcholine and phosphatidylethanolamine in the brain, lungs and liver, as well as by the increase of the content of phosphatidic acid and phosphatidylinositol in tissues. No negative cross-adaptation was found to hypoxic hypoxia and low temperatures.
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