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Efficacy of sweeteners and sugar substitutes in caries prevention
1Department of Preventive Dentistry, Periodontology and Cariology, University of Zurich, Switzerland.
Caries Research
|January 1, 1993
Abstract:
The caries-preventive efficacy of sweeteners and sugar substitutes is not clearly established on an epidemiological scale. A review of cariogenicity assessments in vitro and in vivo as well as of human clinical caries trials, however, clearly demonstrates that the replacement of sugar by such products has a caries-preventive effect. The clinical relevance of some bacteriostatic and/or cariostatic properties ascribed to saccharin, aspartame, and xylitol remains to be corroborated.