The prevalence of insulin resistance in essential hypertension
K Stefíková1, V Spustová, Z Jakubovská
1Institute of Preventive and Clinical Medicine, Bratislava, Slovakia.
Abstract:
The prevalence of insulin resistance and/or glucose intolerance (IR/GI) was evaluated in 98 patients with essential hypertension of various stages: a) Almost 35% of them had an abnormal or diabetic glucose tolerance test and 47% of the total number suffered from either/both IR/GI. b) The prevalence was high from stage I essential hypertension, which pointed to an early development of IR/GI, and no further increase during the development of hypertension was found if no antihypertensive drugs influencing IR/GI were taken by the patients. c) Obesity doubled the prevalence of IR/GI. d) No changes in total and HDL cholesterol or triglycerides were found in patients with IR/GI or stage-dependent. e) The presented criteria could be used for the diagnosis of IR/GI in clinical practice.
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