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Updated: Aug 19, 2026

An Ex vivo Model to Study Hormone Action in the Human Breast
Published on: January 8, 2015
Selective screening of hormonodependent tumours in women's reproductive system organs
V V Kuznetzov1, V F Semiglazov, Maximov SYa
1Turkmen Research Institute of Oncology (Ashkhabad), Russia.
Abstract:
The study is devoted to research of the selective screening possibilities for revealing of hormonodependent tumours of the reproductive system organs in women (endometrial carcinoma, ovarian and breast cancer). The detection of risk factors of cervix uteri cancer, endometrial carcinoma, ovarian and breast cancer has been carried out with the help of a case-control study (311 patients with cancer and 14,872 controls). On the basis of the established risk factors by means of mathematical methods the optimized calculation programmes of individual risks and models in the formation of risk groups of hormonodependent tumours (control 0.32%) have been detected. Through this approach the practical significance of hormonedependent tumours of the selective screening of the reproductive system organs in women has been augmented.

