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Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
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Altered small intestinal smooth muscle function in Crohn's disease

D L Vermillion1, J D Huizinga, R H Riddell

  • 1Intestinal Disease Research Unit, McMaster University Medical Centre, Hamilton, Ontario, Canada.

Gastroenterology
|June 1, 1993
PubMed
Summary

Inflammation in Crohn's disease alters intestinal muscle contractility. Specifically, carbachol and histamine receptor-mediated contractions are significantly changed in the small bowel muscle of patients with this condition.

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