Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Texture perception and afferent coding distorted by cooling the human ulnar nerve

J R Phillips1, P B Matthews

  • 1University Laboratory of Physiology, Oxford, United Kingdom.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|June 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of a patella clamp for femoral head allograft preparation.

Annals of the Royal College of Surgeons of England·2021
Same author

Hemodynamic determinants of aortic dissection propagation by 2D computational modeling: implications for endovascular stent-grafting.

The Journal of cardiovascular surgery·2012
Same author

Acute mesenteric occlusion.

American journal of surgery·2010
Same author

Funnel chest; report of case successfully treated by chondro-sternal resection.

Medical record and annals·2010
Same author

Paroxysmal hypertension due to paraganglioma.

American journal of surgery·2010
Same author

Identification of further Craterostigma plantagineum cdt mutants affected in abscisic acid mediated desiccation tolerance.

Molecular genetics and genomics : MGG·2005
Same journal

Vestibular function drives gaze stability in locomoting macaques.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Region- and layer-specific glutamatergic synapse development in the nascent cortical hierarchy.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Endogenous peptide derived from c-Cbl-associated protein counteracts its inhibitory effect on enteric neural crest cell colonization in Hirschsprung disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Drowsiness alters the neural dynamics but not the core computations of multisensory integration.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

A Matter of Parameters: Tailored Transcranial Focused Ultrasound Enhances Cortico-Thalamo-Cortical Circuit Resonance.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same journal

Proactive visual and motor prioritization differentially scale with cue reliability.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
See all related articles

Cooling the ulnar nerve reduces perceived surface roughness by impairing high-frequency nerve signal transmission. This phenomenon, known as Wedensky inhibition, impacts how the brain processes tactile information.

Area of Science:

  • Neuroscience
  • Psychophysics
  • Somatosensation

Background:

  • Tactile perception of surface roughness is crucial for object interaction.
  • Nerve conduction properties significantly influence sensory processing.

Purpose of the Study:

  • To investigate the impact of localized ulnar nerve cooling on the perception of surface roughness.
  • To determine the underlying neural mechanisms responsible for altered tactile sensation.

Main Methods:

  • Standardized surfaces (dot arrays, gratings) were scanned with the little finger under unilateral ulnar nerve cooling.
  • Electromyography (EMG) monitored axonal conduction during psychophysical testing.
  • Mathematical modeling analyzed the effect of refractory period changes on afferent signals.

Related Experiment Videos

Main Results:

  • Cooling the ulnar nerve made surfaces feel smoother.
  • Wedensky inhibition, not temporal dispersion, was identified as the cause of reduced roughness perception.
  • Large myelinated axons remained conductive but could not sustain high-frequency impulse trains.

Conclusions:

  • Reduced perceived roughness is attributed to Wedensky inhibition affecting high-frequency nerve impulse transmission.
  • The perception of roughness is linked to the spatiotemporal contrast within afferent neural signals.