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Antiinflammatory activity of isomeric phenylnaphthaleneacetic acids

J S Kaltenbronn

Journal of Medicinal Chemistry

|April 1, 1977

Abstract:

The isomeric phenylnaphthaleneacetic acids were prepared and tested for antiinflammatory activity by the anti-UV-erythema method. High potency was exhibited by 4- and 5-phenyl-1-naphthaleneacetic acid and 5- and 6-phenyl-2-naphthaleneacetic acid. The results are discussed in terms of a hypothetical receptor site.

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