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Updated: Sep 16, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
[Maternal, medical and obstetric complications are major risk factors for low birth weight infant]
1Second Affiliated Hospital of Tianjan Medical College.
The risk factors of low birth weight infant (LBW) were prospectively studied in 26,941 pregnant women. Investigations included sociodemographic risks, environmental behavioural conditions, medical diseases before pregnancy and current pregnancy complications. The adjusted odds ratios for various risk factors were calculated from multiple logistic regression model. In this analysis, placenta abnormalities uterine malformations and pregnancy-induced hypertension were shown to be the main risk factors. Preterm delivery occurred more frequently in women with diabetes and injuries in the third trimester. Term SGA babies were usually seen in women who had inadequate diet during pregnancy or in women with maternal heart disease. The risk factors of maternal age, educational background, parental smoking etc were less important than maternal diseases or pregnancy complications. The present study indicated prenatal care, started early with regular check-ups was mast important in preventing prematurity and LBW infant in China.
The risk factors of low birth weight infant (LBW) were prospectively studied in 26,941 pregnant women. Investigations included sociodemographic risks, environmental behavioural conditions, medical diseases before pregnancy and current pregnancy complications. The adjusted odds ratios for various risk factors were calculated from multiple logistic regression model. In this analysis, placenta abnormalities uterine malformations and pregnancy-induced hypertension were shown to be the main risk factors. Preterm delivery occurred more frequently in women with diabetes and injuries in the third trimester. Term SGA babies were usually seen in women who had inadequate diet during pregnancy or in women with maternal heart disease. The risk factors of maternal age, educational background, parental smoking etc were less important than maternal diseases or pregnancy complications. The present study indicated prenatal care, started early with regular check-ups was mast important in preventing prematurity and LBW infant in China.
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