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Effect of type II diabetes mellitus on cognitive function
G Worrall1, N Moulton, E Briffett
1Medical Clinic, Glovertown, Newfoundland, Canada.
The Journal of Family Practice
|June 1, 1993
Summary
Elderly individuals with non-insulin-dependent diabetes mellitus (NIDDM) show poorer cognitive function. This study found significant differences in memory and cognitive tests between NIDDM patients and a matched control group.
Area of Science:
- Gerontology
- Neuroscience
- Endocrinology
Background:
- Diabetes mellitus is associated with neurological complications like peripheral and autonomic neuropathy.
- Cognitive deficits may also be a consequence of diabetes mellitus.
Purpose of the Study:
- To compare cognitive function in elderly individuals with non-insulin-dependent diabetes mellitus (NIDDM) against a matched control group.
- To investigate the potential link between NIDDM and cognitive impairment in older adults.
Main Methods:
- A study involving 90 elderly outpatients with NIDDM and 90 matched nondiabetic individuals.
- Cognitive function was assessed using the Modified Mini-Mental State (3MS) and Delayed Word Recall (DWR) tests.
Main Results:
- Individuals with NIDDM scored significantly lower on the 3MS test (mean 75.6) compared to controls (mean 79.5).
- NIDDM patients also demonstrated lower scores on the DWR test (mean 3.9) versus controls (mean 4.7).
Conclusions:
- Non-insulin-dependent diabetes mellitus is associated with a measurable decline in cognitive function.
- Healthcare providers should consider the impact of type 2 diabetes on cognitive abilities in elderly patients.