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Second malignant neoplasms after treatment for osteosarcoma: a report of three cases
1Department of Orthopaedic Surgery, Okayama University Medical School, Japan.
Acta Medica Okayama
|April 1, 1993
Abstract:
We report second malignant neoplasms which developed between 7 and 19 years after treatment in 3 pediatric patients with osteosarcoma. Two patients had been treated with only surgery, and another patient had been treated with a combination of surgery with chemotherapy and radiation therapy for primary lesions. Pediatric patients with osteosarcoma, in particular, require careful long-term follow-up to monitor not only metastases but also development of second malignant neoplasms.