Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Shock induced ethanol consumption in rats

K C Mills, J W Bean, J S Hutcheson

    Pharmacology, Biochemistry, and Behavior
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Impact of California Fires on Local and Regional Air Quality: The Role of a Low-Cost Sensor Network and Satellite Observations.

    GeoHealth·2019
    Same author

    I have spikes on my hands.

    Clinical and experimental dermatology·2011
    Same author

    Chronic motor disability resulting from repeated exposure to oxygen at high pressure.

    Federation proceedings·2010
    Same author

    Adverse influence of increased oxygen pressure on malarial parasites in vitro and in vivo.

    Federation proceedings·2010
    Same author

    Degenerative changes in the C.N.S. of albino rats by exposure to 02 at high pressure.

    Federation proceedings·2010
    Same author

    Further observations on red cell agglutinating agent present in lungs of virus-infected mice.

    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)·2010

    Rats increased ethanol consumption after experiencing inescapable shock, suggesting a link between stress and alcohol intake. This effect was observed with different ethanol concentrations and persisted even when other fluids were available.

    Area of Science:

    • Neuroscience
    • Behavioral Science
    • Pharmacology

    Background:

    • Stress and anxiety are known contributors to substance use disorders.
    • Understanding the behavioral responses to stress can provide insights into addiction mechanisms.

    Purpose of the Study:

    • To investigate the effects of inescapable stress on voluntary ethanol consumption in rats.
    • To determine if stress exposure alters ethanol intake patterns and preferences.

    Main Methods:

    • Two experiments were conducted using rats exposed to recurring schedules of inescapable random shock.
    • Experiment 1: Rats chose between ethanol (5% and 10% V/V) and water.
    • Experiment 2: Rats had access to water, saccharin, 5% ethanol, and 10% ethanol during extended stress sessions.

    Related Experiment Videos

    Main Results:

    • Rats significantly increased ethanol consumption immediately following stress exposure in both experiments.
    • The increase in ethanol intake was specific to the presence of shock and not observed in total daily intake.
    • Rats showed a preference shift towards higher ethanol concentrations (10%) over time under stress, while saccharin and water intake decreased.

    Conclusions:

    • Inescapable stress triggers an immediate increase in voluntary ethanol consumption in rats.
    • Ethanol intake may serve as a coping mechanism to alleviate the negative consequences of stress.
    • These findings highlight a potential role for ethanol in stress-induced behavioral responses.