Search research articles

Search research articles

Related Experiment Videos

Latex hypersensitivity: a case study

S N Mathew¹, A L Melton, W O Wagner

¹Cleveland Clinic Foundation, OH 44195.

Annals of Allergy

|June 1, 1993

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Content validation using an expert panel: assessment process for assistive technology adopted by farmers with disabilities.

Journal of agricultural safety and health·2011

Same author

Angioedema: frightening and frustrating.

Cleveland Clinic journal of medicine·1999

Same author

Differential regulation of human blood monocyte and alveolar macrophage inflammatory cytokine production by nitric oxide.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·1999

Same author

Managing latex allergy in patients and health care workers.

Cleveland Clinic journal of medicine·1997

Same author

Shared IgE-binding sites among separated components of natural rubber latex.

International archives of allergy and immunology·1996

Same author

Latex hypersensitivity in emergency medical service providers.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·1996

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Skin prick testing is the preferred diagnostic method for latex allergy, showing higher sensitivity than in vitro IgE testing. This study highlights the effectiveness of skin prick tests in diagnosing latex sensitivity.

Area of Science:

Immunology
Allergy and Immunology
Dermatology

Background:

Latex allergy is a significant concern, particularly during medical procedures.
Manifestations include anaphylaxis and contact urticaria.
Accurate diagnostic methods are crucial for patient safety.

Purpose of the Study:

To evaluate diagnostic methods for latex allergy.
To compare the sensitivity of skin prick tests versus in vitro IgE testing.

Main Methods:

Retrospective analysis of 16 latex allergy cases.
Skin prick testing performed on all subjects and 10 controls.
In vitro analysis using ELISA for latex-specific IgE.

Main Results:

Related Experiment Videos

Skin prick tests were positive in all 16 subjects and negative in 10 controls.
ELISA for latex-specific IgE was positive in only 3 subjects.
No adverse reactions were reported during testing.

Conclusions:

Skin prick testing is a highly sensitive and preferred method for diagnosing latex allergy.
The in vitro ELISA method demonstrated an unacceptable lack of sensitivity in this study.
Early and accurate diagnosis of latex allergy is essential to prevent severe reactions.