Related Experiment Video
Updated: Aug 3, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
Patients with atopic eczema do become sensitized to contact allergens
1St John's Institute of Dermatology, St Thomas's Hospital, London, UK.
Abstract:
Sensitization to contact allergens in atopics was assessed by grouping 989 patients, who were routinely patch tested, by their personal atopic status. Sensitization to > or = 1 allergens occurred in 38% of the 191 patients with existing atopic eczema, in 53% of the 120 with a past history of atopic eczema, in 54% of the 156 with only mucous membrane atopy and in 50% of the 510 who were not atopic. Sensitization to perfume, a common environmental allergen, was similar in all 4 groups, as was nickel among women. Patients with atopic eczema should be patch tested.
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