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Updated: Aug 12, 2026

Rapid Analysis of Chromosome Aberrations in Mouse B Lymphocytes by PNA-FISH
07:54

Rapid Analysis of Chromosome Aberrations in Mouse B Lymphocytes by PNA-FISH

Published on: August 19, 2014

Complementation analysis in ataxia telangiectasia: fibroblast-lymphoblastoid cell heterokaryon assay by

P Chen1, C Kidson

  • 1Queensland Cancer Fund Research Unit, Queensland Institute of Medical Research, Brisbane, Australia.

Cytogenetics and Cell Genetics
|January 1, 1993
PubMed

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Related Concept Videos

Complementation Tests00:49

Complementation Tests

A complementation test is a simple cross to identify whether the two mutations are located on the same gene or different genes. It was first performed by Edward Lewis in the 1940s while working on fruit flies. He developed the test to identify the location and arrangement of different mutations on chromosomes.
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...