Motion-induced aversions during and after recovery from olfactory nerve section in mice

Bilaterally nerve-sectioned male albino mice were given access to a novel food (almond) and then body rotated for 50 min. Two days later the mice were given a second access to almond. The procedures were repeated after recovery of olfactory function. Mice formed a presumably taste-mediated aversion while anosmic and a second flavor-mediated aversion (to the same food) after the return of olfactory function. Rotation control subjects formed only the standard flavor aversion subsequent to the first pairing of novel food and motion. It appears that olfaction is required for recognition of a food as novel.