Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hairy-cell leukemia]

E E Damasio1, T Lamparelli, F Chimirri

  • 1I Divisione di Ematologia, Ospedale San Martino, Genova.

Recenti Progressi in Medicina
|May 1, 1993
PubMed
Summary

This review covers hairy-cell leukemia diagnosis and treatment, detailing clinical features, diagnostic methods, and evolving therapeutic strategies including purine analogues. It also addresses minimal residual disease and variants.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unmanipulated haploidentical bone marrow transplantation and post-transplant cyclophosphamide for hematologic malignanices following a myeloablative conditioning: an update.

Bone marrow transplantation·2015
Same author

DLI after haploidentical BMT with post-transplant CY.

Bone marrow transplantation·2014
Same author

Outcome of patients activating an unrelated donor search: the impact of transplant with reduced intensity conditioning in a large cohort of consecutive high-risk patients.

Leukemia·2012
Same author

In vivo B-cell depletion with rituximab for alternative donor hemopoietic SCT.

Bone marrow transplantation·2011
Same author

Risk factors for enterococcal bacteremia in allogeneic hematopoietic stem cell transplant recipients.

Transplant infectious disease : an official journal of the Transplantation Society·2010
Same author

Pre-emptive treatment of acute GVHD: a randomized multicenter trial of rabbit anti-thymocyte globulin, given on day+7 after alternative donor transplants.

Bone marrow transplantation·2009

Area of Science:

  • Hematology
  • Oncology

Context:

  • Hairy-cell leukemia (HCL) is a rare B-cell chronic lymphoid leukemia.
  • Understanding its diagnosis and treatment is crucial for patient outcomes.

Purpose:

  • To provide a comprehensive review of current opinions on HCL diagnosis and treatment.
  • To analyze the impact of various therapeutic strategies on disease management.

Summary:

  • Details clinical and hematological characteristics, diagnostic features (morphological, cytochemical, cytogenetic, histological, immunophenotypic), differential diagnosis, and prognostic factors.
  • Reviews current treatments, including splenectomy, alpha-interferon, and purine analogues (2-CdA, 2-dCF), based on Italian Cooperative Group studies and published data.
  • Discusses minimal residual disease, second neoplasia, causes of death, and HCL variants.

Impact:

  • Highlights the evolution of prognostic factors and therapeutic strategies in HCL management.
  • Emphasizes the significant impact of newer drugs like purine analogues on HCL treatment.
  • Provides a consolidated resource for clinicians and researchers on HCL.

Related Experiment Videos