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Related Experiment Videos

Piezoelectric shockwave lithotripters: differences in fragmentation efficiency in vitro

H T Schneider1, E Weisshaar, A Anderegg

  • 1Dept. of Medicine I, University of Erlangen-Nuremberg, Germany.

Scandinavian Journal of Gastroenterology
|May 1, 1993
PubMed
Summary

The Piezolith 2300 effectively disintegrated all human gallstones in vitro, unlike the EDAP LT.01 and Therasonic lithotripters. This piezoelectric lithotripter required fewer shockwave pulses for stone fragmentation compared to the other devices tested.

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Area of Science:

  • Urology
  • Medical Devices
  • Nephrology

Background:

  • Gallstone fragmentation is crucial for non-invasive treatment.
  • Piezoelectric lithotripsy offers a potential method for gallstone disintegration.
  • Comparative studies are needed to evaluate the efficacy of different lithotripter devices.

Purpose of the Study:

  • To compare the stone fragmentation efficacy of three piezoelectric lithotripters: Piezolith 2300, EDAP LT.01, and Therasonic.
  • To assess the number of shockwave pulses required for successful gallstone disintegration.

Main Methods:

  • In vitro disintegration of 72 human gallstones using Piezolith 2300, EDAP LT.01, and Therasonic.
  • Gallstones were categorized into two groups based on diameter (6-15 mm and 16-25 mm).

Related Experiment Videos

  • Lithotripters were operated at maximum energy settings, with treatment ending at < or = 4 mm fragments or 6000 pulses.

    • Main Results:

    • Piezolith 2300 successfully disintegrated all gallstones to < or = 4 mm fragments.
    • EDAP LT.01 and Therasonic failed to fragment 2 and 6 stones, respectively, even after 6000 pulses.
    • Piezolith 2300 required significantly fewer pulses for fragmentation in both stone size groups compared to EDAP LT.01 and Therasonic (p < 0.01 and p < 0.05).

    Conclusions:

    • The Piezolith 2300 demonstrates superior gallstone fragmentation efficacy compared to EDAP LT.01 and Therasonic.
    • Fewer shockwave pulses are needed with the Piezolith 2300 for effective stone disintegration.
    • The Piezolith 2300 presents a more efficient option for in vitro piezoelectric gallstone lithotripsy.