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[Heroin addicts in substitution programs]

T Baumann1, R Battegay, U Rauchfleisch

  • 1Psychiatrische Universitätspoliklinik, Kantonsspital, Basel.

Schweizerische Medizinische Wochenschrift
|May 22, 1993
PubMed
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Hydrocodone and methadone maintenance therapy significantly reduced criminality and prostitution in heroin addicts, with stable employment rates. Therapeutic success did not differ between hydrocodone and methadone treatments.

Area of Science:

  • Addiction Medicine
  • Pharmacology
  • Public Health

Background:

  • Opioid dependence remains a significant global health challenge.
  • Maintenance therapy is a cornerstone in managing heroin addiction.
  • Evaluating alternative medications like hydrocodone is crucial for treatment efficacy.

Purpose of the Study:

  • To compare the effectiveness of hydrocodone (Dicodid) versus methadone in heroin addiction maintenance therapy.
  • To assess the impact of these therapies on criminality, prostitution, and employment.
  • To determine if patient reliability influences therapeutic outcomes.

Main Methods:

  • A standardized interview was conducted with 40 heroin addicts.
  • 20 patients received hydrocodone maintenance therapy, and 20 received methadone.

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  • Data collected included patient history, current situation, employment status, criminality, and prostitution.

    • Main Results:

    • Both hydrocodone and methadone groups showed a significant reduction in criminality and prostitution.
    • Employment rates remained stable across both treatment groups.
    • No significant differences in therapeutic success were observed between hydrocodone and methadone, irrespective of patient reliability.

    Conclusions:

    • Hydrocodone is a viable alternative to methadone for heroin addiction maintenance therapy.
    • The choice of medication did not impact key therapeutic outcomes like reduced crime and prostitution.
    • Hydrocodone can be recommended for relatively reliable heroin addicts in maintenance therapy.