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Published on: November 19, 2020
Adjuvant activity of the Escherichia coli WF table L-form cytoplasmic membranes
E Ivanova1, B Kenarova, J Gumpert
1Institute of Microbiology, Bulgarian Academy of Sciences.
Abstract:
It was established that the stable E. coli WF+ L-form cytoplasmic membranes (CM) increase the antibody response in rabbit during experimental hyperimmunization with cells of Streptococcus pyogenes A49 and Proteus mirabilis D52. Using the skin-induration test and the reaction for aggregation of macrophages in presence of homologous antigens it was established that CM increase the cell-mediated immunity of guinea-pigs to protein antigens of the same bacterial strains.
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