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Related Experiment Videos

Does a safe size-limit exist for unruptured intracranial aneurysms?

J Rosenørn1, V Eskesen

  • 1University Clinic of Neurosurgery, Copenhagen County Hospital, Glostrup, Denmark.

Acta Neurochirurgica
|January 1, 1993
PubMed
Summary

Ruptured intracranial aneurysms (RA) were analyzed by size. The study suggests operating on unruptured aneurysms 10 mm or smaller, as size did not significantly correlate with rupture timing within 10 days.

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Area of Science:

  • Neurosurgery
  • Vascular Neurology
  • Radiology

Background:

  • Intracranial ruptured aneurysms (RA) pose a significant health risk.
  • Accurate assessment of RA size is crucial for treatment decisions.
  • The Danish Aneurysm Study provides a large dataset for analysis.

Purpose of the Study:

  • To investigate the relationship between the size of intracranial ruptured aneurysms and their rupture.
  • To evaluate the reliability of aneurysm diameter as an indicator of rupture timing.
  • To inform surgical recommendations for unruptured aneurysms based on size.

Main Methods:

  • Analysis of 1076 patients with intracranial ruptured aneurysms from the Danish Aneurysm Study.
  • Angiographic verification of 948 ruptured aneurysms.

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  • Categorization of aneurysm diameters: <5 mm (162), 5-10 mm (474), and 11-24 mm (272).
  • Statistical assessment of aneurysm diameter in relation to the day of angiography post-rupture.

    • Main Results:

    • 908 of the verified ruptured aneurysms had a maximum diameter less than 25 mm.
    • Aneurysm diameter did not significantly differ based on the day of angiography within the first 10 days post-rupture.
    • This suggests size is an indirect, potentially unreliable, indicator of rupture timing.

    Conclusions:

    • Aneurysm size alone is not a reliable predictor of the timing of rupture within the initial 10 days.
    • Unruptured aneurysms measuring 10 mm or less warrant serious consideration for surgical intervention.
    • This recommendation aims to mitigate the risk associated with potential future rupture.