A structured compartmental model for drug kinetics
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1Department of Mathematics, University of Queensland, Brisbane, Australia.
Biometrics
|March 1, 1993
Abstract:
A compartmental model with a structure that describes drug kinetics by incorporating the ideas of diffusion and gamma distributed clearance times is proposed. The equations describing this model may be solved by elementary numerical techniques, and the model is shown to fit a data set describing renal gentamicin concentrations, better than a simple power-function model.