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Prognostic factors in typhoid perforation

J A Akoh1

  • 1Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.

East African Medical Journal
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

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Surgery for typhoid perforation in Nigeria showed high mortality. Early presentation, diagnosis, resuscitation, and prompt surgical intervention are crucial for improving patient outcomes in typhoid perforation cases.

Area of Science:

  • Medicine
  • Surgery
  • Infectious Diseases

Background:

  • Typhoid perforation is a severe complication of Salmonella Typhi infection.
  • Surgical management is often required for intestinal perforations caused by typhoid fever.

Purpose of the Study:

  • To review surgical outcomes for typhoid perforation.
  • To identify prognostic factors influencing mortality in patients with typhoid perforation.

Main Methods:

  • Retrospective review of 60 patients undergoing surgery for typhoid perforation.
  • Data collected on patient demographics, surgical procedures, and outcomes.

Main Results:

  • Solitary ileal perforation was the most common presentation (78%).

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  • Simple closure with debridement was the primary surgical approach (87%).
  • Overall hospital mortality was high at 57%.

    • Conclusions:

    • High mortality associated with typhoid perforation underscores the need for timely intervention.
    • Early presentation, diagnosis, aggressive resuscitation, and prompt surgery are vital for improving prognosis.