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Similarity of DNA fingerprints due to chance and relatedness
C C Li1, D E Weeks, A Chakravarti
1Department of Human Genetics, Graduate School of Public Health, University of Pittsburg, Pa. 15261.
Human Heredity
|January 1, 1993
Abstract:
Given the DNA fingerprints of two individuals with some bands being shared by both individuals, we define a new measure of the degree of similarity between the DNA profiles of two individuals. We use this measure to calculate the expected DNA similarity of two unrelated individuals of a randomly mating population; this similarity is due to chance only. Then, the expected similarity between two related individuals is obtained; this similarity is due to chance and relatedness. From these results, the degree of similarity due to relatedness alone may be calculated.