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Antimicrobial activity of two bactenecins against spirochetes
1Department of Biochemistry, Biophysics and Macromolecular Biochemistry, University of Trieste, Italy.
Infection and Immunity
|July 1, 1993
Abstract:
Bac5 and Bac7 are antimicrobial peptides of bovine neutrophils that act on enteric gram-negative bacteria. We report here that these two peptides immobilize and kill Leptospira interrogans and Leptospira biflexa with MBCs of 6 to 25 micrograms/ml. Conversely, although both peptides bind to Borrelia burgdorferi, the organism is resistant to their action.