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Amino-terminal sequence analysis of the Coccidioides immitis chitinase/immunodiffusion-complement fixation protein
S M Johnson1, C R Zimmermann, D Pappagianis
1Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis 95616.
Abstract:
A chitinase isolated from Coccidioides immitis was subjected to amino-terminal protein sequence analysis. The resulting 18-amino-acid sequence was compared with the previously reported amino acid sequence of coccidioidal immunodiffusion-complement fixation (IDCF) antigen. From the homology of the two sequences, the results support the identification of the IDCF antigen with a chitinase.
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