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Reflex sympathetic dystrophy syndrome

L S Osher1, G J Young, A A Edwards

  • 1Ohio College of Podiatric Medicine, Cleveland 44106.

Journal of the American Podiatric Medical Association
|May 1, 1993
PubMed
Summary
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Reflex sympathetic dystrophy syndrome, now known as complex regional pain syndrome, causes severe pain disproportionate to injury. Its etiology involves vascular reflex spasms, vasodilation, and bone loss after trauma.

Area of Science:

  • Pain Medicine
  • Neurology
  • Orthopedics

Background:

  • Reflex sympathetic dystrophy syndrome (RSDS) is a complex disorder characterized by severe, unexplained pain.
  • Pain intensity is often disproportionate to the initial injury, posing diagnostic challenges.

Observation:

  • Genant et al. described six diagnostic criteria for RSDS: extremity pain/tenderness, soft tissue swelling, reduced motor function, skin changes, vasomotor instability, and osteoporosis.
  • The condition involves chronic, aching, or burning pain sensations.

Findings:

  • The most accepted etiology involves an initial vasomotor reflex spasm post-injury.
  • This is followed by a loss of vascular tone, sustained vasodilation, and accelerated bone resorption.

Implications:

Related Experiment Videos

  • Understanding RSDS etiology is crucial for developing targeted treatments.
  • Improved diagnostic criteria aid in earlier and more accurate patient identification.
  • Further research into vasomotor dysregulation can unlock novel therapeutic strategies.