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[Endoscopic classification of healing process in tracheobronchial tuberculosis]
T Rikimaru1, Y Tanaka, Y Ichikawa
1First Department of Internal Medicine, Kurume University School of Medicine.
Nihon Kyobu Shikkan Gakkai Zasshi
|April 1, 1993
Summary
Tracheobronchial tuberculosis healing progresses through active, healing, and scarring stages over at least three months. Aerosol streptomycin may accelerate healing of these active tuberculosis lesions.
Area of Science:
- Pulmonology
- Infectious Diseases
- Endoscopy
Context:
- Tracheobronchial tuberculosis is a severe form of tuberculosis affecting the airways.
- Diagnosis and monitoring of healing stages are crucial for effective treatment.
Purpose:
- To classify and describe the healing stages of tracheobronchial tuberculosis lesions.
- To evaluate the progression of lesions during antitubercular treatment.
- To determine the time required for healing and the impact of aerosol therapy.
Summary:
- Bronchofiberoscopic examination of 41 patients with active tracheobronchial tuberculosis revealed three healing stages: Active (A), Healing (H), and Scarring (S).
- Lesions progressed from stage A to H to S during treatment with standard antitubercular agents (isoniazid, rifampicin, streptomycin/ethambutol).
- Sputum smear and culture positivity decreased significantly across stages A, H, and S, with stage S showing 0% culture positivity.
Impact:
- Establishes a clear progression of healing stages for tracheobronchial tuberculosis, aiding clinical assessment.
- Suggests a minimum of three months for ulcerous lesion healing, with potential acceleration by aerosol streptomycin therapy.
- Provides evidence for the efficacy of standard antitubercular regimens in healing airway tuberculosis.