Informational analysis of morphometric parameters of pulmonary heart in chronic nonspecific pulmonary diseases

The difference between macro- and micrometric parameters of the right ventricle of the heart was studied in 26 autopsy cases of chronic nonspecific pulmonary disease, and 11 cases of violent death without pulmonary or cardiac disease from the institute of forensic medicine, matching in age and sex with the first group. The results obtained from organ and tissue analysis enabled us to determine the most informative parameters common for compensation and decompensation status of cor pulmonale: Width, wall thickness, and weight of the right ventricle, thickness of cardiomyocytes and cross-section of their nuclei. Analysis of morphometric parameters at the compensation stage revealed a specific diagnostic value in the circumference of the pulmonary artery and the volume density of focal cardiomyocytic lesions. For the decompensation stage, it was possible to gain specific diagnostic information from the length of inflow into the right ventricle, and from the volume and density of sclerotic foci.