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Famotidine for gastric radiography
1Department of Radiology, Faculty of Medicine, University of Tokyo, Japan.
Radiation Medicine
|January 1, 1993
Summary
Famotidine effectively reduces nighttime stomach acid production, improving the quality of gastric imaging for diagnostic procedures. This pretreatment enhances radiograph clarity for barium meal examinations.
Area of Science:
- Gastroenterology
- Radiology
- Pharmacology
Background:
- Nocturnal gastric secretion can interfere with diagnostic imaging of the stomach.
- Optimizing gastric preparation is crucial for accurate radiological examinations.
Purpose of the Study:
- To evaluate the efficacy of famotidine in suppressing nocturnal gastric secretion.
- To assess the impact of famotidine pretreatment on the quality of gastric radiography.
Main Methods:
- A study involving 243 patients undergoing gastric radiography.
- Gastric juice volume was determined using a single upright radiograph.
- Comparison between a famotidine group and a control group.
Main Results:
- Famotidine achieved an overall 60% suppression of nocturnal gastric secretion.
- Patients receiving famotidine showed a higher diagnostic quality rate (91%) compared to controls (82%).
- Improved image quality was observed in the famotidine group, with 45% excellent films versus 3% in controls.
Conclusions:
- Famotidine is effective in reducing nocturnal gastric acid production.
- Famotidine pretreatment can significantly enhance the diagnostic quality of barium meal examinations.
- Famotidine is a potentially useful agent for preparing patients for gastric radiography.