Malignant melanoma: differential diagnosis of the pigmented lesion

Familiarity with the clinical signs of malignant melanoma can result in earlier recognition and thus potentially decrease both patient morbidity and mortality. Unfortunately, several cutaneous tumors, both benign and malignant, have clinical similarities to this neoplasm, often making the correct diagnosis difficult. The purpose of this paper is to discuss the clinical characteristics of the different types of malignant melanoma and those lesions that mimic this ominous malignancy. Furthermore, diagnostic clues to help delineate between these various pigmented lesions are provided.