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[Arterial hypertension in the elderly and renal function]
L M Falcão1, P Alcântara, J G Clara
1GITHI, Serviço de Medicina I, Hospital de Santa Maria, Faculdade de Medicina, Lisboa.
Study Objective:
to evaluate the effects of antihypertensive treatment on renal function, in an elderly population of 29 patients with arterial hypertension.
Design:
retrospective study of the first six months follow-up.
Setting:
outpatients clinic of arterial hypertension in the elderly at a central hospital.
Patients And Methods:
twenty nine elderly (> or = 65 years old) patients with a mean age of 71.8 +/- 5.6 years, with arterial hypertension (> or = 160/95 mmHg) submitted to antihypertensive treatment. Fourteen males and fifteen females. The systolic, diastolic and mean blood pressure was determined with a DINAMAP 1846, previously and at the first, third and sixth month of antihypertensive treatment (diuretic, calcium antagonists and angiotensin converting enzyme inhibitors). The serum creatinine was evaluated in the beginning of treatment and six months later. Means (+/- standard deviation) were compared with Student's t-test (statistically significant findings < 0.05).
Measurements And Results:
the initial mean arterial pressure was 127.0 +/- 17 mmHg; with the antihypertensive treatment, was 119.1 +/- 16 mmHg in the first month, 114.4 +/- 12 mmHg in the third and 117.6 +/- 12 mmHg in the sixth month. The serum creatinine was 1.26 +/- 0.75 mg/dl in the beginning of the study and the final result was 1.30 +/- 0.74 mg/dl (p-NS).
Conclusions:
the antihypertensive treatment was effective in reducing the blood pressure, without a significant increase in serum creatinine.