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[Arterial hypertension in the elderly and renal function]

L M Falcão1, P Alcântara, J G Clara

  • 1GITHI, Serviço de Medicina I, Hospital de Santa Maria, Faculdade de Medicina, Lisboa.

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
|January 1, 1993
PubMed
Summary

Antihypertensive treatment effectively reduced blood pressure in elderly patients with hypertension. Renal function, measured by serum creatinine, remained stable, showing no significant adverse effects from the treatment.

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Area of Science:

  • Nephrology
  • Geriatrics
  • Cardiology

Background:

  • Arterial hypertension is a prevalent condition in the elderly.
  • Maintaining renal function is crucial during antihypertensive therapy in older adults.

Purpose of the Study:

  • To assess the impact of antihypertensive treatment on renal function in elderly patients.
  • To evaluate the safety and efficacy of blood pressure management in this demographic.

Main Methods:

  • A retrospective study involving 29 elderly patients (≥65 years) with arterial hypertension.
  • Blood pressure was monitored for six months during treatment with diuretics, calcium antagonists, or ACE inhibitors.
  • Serum creatinine levels were measured at baseline and after six months.

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Main Results:

  • Antihypertensive treatment significantly reduced mean arterial pressure from 127.0 mmHg to 114.4 mmHg by the third month.
  • Serum creatinine levels showed no statistically significant change, remaining stable throughout the study period.
  • The observed changes in blood pressure and creatinine were not statistically significant (p-NS).

Conclusions:

  • Antihypertensive treatment is effective in controlling blood pressure in elderly hypertensive patients.
  • The studied antihypertensive regimens appear safe for renal function in this population.
  • Further long-term studies are warranted to confirm these findings.