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[Atypical early infantile epileptic encephalopathy with suppression-burst]
Insights
This study details an infant with early infantile epileptic encephalopathy exhibiting tonic spasms and suppression-burst electroencephalogram (EEG) patterns. The findings highlight a rare epilepsy syndrome with distinct EEG characteristics.
Area of Science:
- Pediatric Neurology
- Clinical Electrophysiology
Abstract:
We report an 8-month-old infant with tonic spasms that started at the age of 38 days and occurred in clusters. He had no myoclonic seizures, or erratic myoclonus. Repeated simultaneous video-EEG monitoring revealed abrupt flexion of the neck and extremities associated with high voltage slow waves preceded by multiple spikes and/or sharps, which resembled spasms seen in West syndrome. Interictal EEGs, before and after the onset of epilepsy, showed suppression-burst. The bursts consisted of irregular high voltage slow waves mixed with poorly developed spike before the onset of epilepsy. On the other hand, duration of suppression phase ranged from 1 to 27 seconds, and burst-burst interval from 2 to 30 seconds after the onset of epilepsy. He was considered as having an atypical early infantile epileptic encephalopathy with suppression burst.