Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Interstitial nephritis in typhus]

V Schumann1, E Fritschka, U Helmchen

  • 1Abteilung für Nieren- und Hochdruckkrankheiten, Universitätsklinikum Essen.

Deutsche Medizinische Wochenschrift (1946)
|June 18, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MMW Fortschritte der Medizin·2019
Same author

MMW Fortschritte der Medizin·2019
Same author

MMW Fortschritte der Medizin·2017
Same author

MMW Fortschritte der Medizin·2016
Same author

[Not Available].

MMW Fortschritte der Medizin·2016
Same author

[Not Available].

MMW Fortschritte der Medizin·2016
Same journal

Deutsche medizinische Wochenschrift (1946)·2026
Same journal

["Not everything that looks like a tumor..." - Pulmonary tularemia with hilar lymphadenopathy].

Deutsche medizinische Wochenschrift (1946)·2026
Same journal

[Emergency management of sickle cell disease].

Deutsche medizinische Wochenschrift (1946)·2026
Same journal

[Hereditary dehydrated stomatocytosis (= hereditary xerocytosis) - Interesting hummingbird or clinically relevant diagnosis?]

Deutsche medizinische Wochenschrift (1946)·2026
Same journal

[Diagnosis of Congenital Hemolytic Anemias in Adults].

Deutsche medizinische Wochenschrift (1946)·2026
Same journal

[46-year-old female patient with right upper abdominal pain].

Deutsche medizinische Wochenschrift (1946)·2026
See all related articles

A patient with typhus experienced acute kidney injury, but recovered after early doxycycline treatment. Prompt antibiotic intervention is crucial for preventing irreversible renal damage in typhus cases.

Area of Science:

  • Infectious Diseases
  • Nephrology
  • Microbiology

Background:

  • Typhus, a rickettsial infection, can present with diverse clinical manifestations.
  • Renal involvement in typhus is a recognized but potentially severe complication.

Observation:

  • A 58-year-old man presented with fever and rash following travel to Rhodos, consistent with typhus.
  • The patient developed acute kidney injury with a significant rise in serum creatinine.
  • Renal biopsy confirmed acute granulomatous interstitial nephritis, indicative of rickettsial infection.

Findings:

  • Early treatment with doxycycline led to rapid improvement in fever and general condition.
  • Despite initial deterioration, renal function recovered following a prolonged course of doxycycline.

Related Experiment Videos

  • Antibody titers against Rickettsia species decreased over time, correlating with clinical recovery.

    • Implications:

    • This case highlights the importance of considering typhus in febrile illnesses with rash, especially after travel to endemic areas.
    • Early diagnosis and prompt antibiotic treatment, such as with doxycycline, are critical for managing typhus and preventing severe complications like acute kidney injury.
    • Timely intervention can lead to favorable renal outcomes and avoid long-term renal damage.