Nonrheumatic conditions in children including infectious diseases and syndromes

L B Tucker1

  • 1Division of Pediatric Rheumatology, Floating Hospital for Children, New England Medical Center, Boston, MA 02111, USA.

Insights

Pediatric rheumatologists often diagnose nonrheumatologic conditions in children. This review covers infections, inherited syndromes, and bony dysplasias affecting the musculoskeletal system.

Area of Science:

  • Pediatric Rheumatology
  • Infectious Diseases
  • Genetics

Background:

  • Many children referred to pediatric rheumatologists have nonrheumatologic conditions.
  • Infections and genetic disorders can significantly impact the musculoskeletal system.
  • Understanding these diverse conditions is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To review nonrheumatologic musculoskeletal disorders in children.
  • To highlight infections, inherited syndromes, and bony dysplasias.
  • To provide an overview of current clinical findings and genetic information.

Main Methods:

  • Literature review of infectious causes of musculoskeletal symptoms.
  • Review of inherited syndromes with musculoskeletal manifestations.
  • Examination of bony dysplasias and rare syndromes affecting children.

Main Results:

  • Infections like Yersinia, tuberculosis, and brucellosis can cause musculoskeletal issues.
  • Reactive arthritis and changing clinical spectra of acute rheumatic fever are noted.
  • Inherited syndromes and bony dysplasias present diverse musculoskeletal findings.

Conclusions:

  • Nonrheumatologic conditions are common in pediatric rheumatology evaluations.
  • Infections and genetic factors play a significant role in pediatric musculoskeletal health.
  • Comprehensive review aids in diagnosing and managing diverse pediatric musculoskeletal disorders.

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