Related Experiment Videos
The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins
O Albagli1, P Dhordain, C Deweindt
1Institut National de la Santé et de la Recherche Médicale U124-IRCL, Lille, France.
Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research
|September 1, 1995
Abstract:
The BTB/POZ domain defines a newly characterized protein-protein interaction interface. It is highly conserved throughout metazoan evolution and generally found at the NH2 terminus of either actin-binding or, more commonly, nuclear DNA-binding proteins. By mediating protein binding in large aggregates, the BTB/POZ domain serves to organize higher order macromolecular complexes involved in ring canal formation or chromatin folding.