Cell counts in peripheral blood and bone marrow of male CBA/N mice

Measurements for blood and bone marrow cell counts were carried out in male CBA/N mice aged 3, 6, 9, 12, and 26 weeks and the values were compared with those in normal mice. In the peripheral blood, CBA/N mice showed decreasing numbers of leukocytes with age, without marked changes in the differential cell count. In the bone marrow of CBA/N mice, the total number of femoral bone marrow cells was low in later life (26 weeks of age), and differential cell counts revealed a high granuloid/erythroid ratio at 3 weeks of age due to a low erythroblast count.