Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

F Delaglio1, S Grzesiek, G W Vuister

  • 1Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Journal of Biomolecular NMR
|November 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Breathing, speaking, coughing or sneezing: What drives transmission of SARS-CoV-2?

Journal of internal medicine·2021
Same author

Neutralization of Interleukin-17 Attenuates Cholestatic Liver Fibrosis in Mice.

Scandinavian journal of immunology·2015
Same author

Control of a chemical reaction (photodegradation of the p3ht polymer) with nonlocal dielectric environments.

Scientific reports·2015
Same author

Curcumin inhibits bovine herpesvirus type 1 entry into MDBK cells.

Acta virologica·2015
Same author

PAK5-mediated E47 phosphorylation promotes epithelial-mesenchymal transition and metastasis of colon cancer.

Oncogene·2015
Same author

Weekly cetuximab concurrent with IMRT aggravated radiation-induced oral mucositis in locally advanced nasopharyngeal carcinoma: Results of a randomized phase II study.

Oral oncology·2015
Same journal

pyTRACTnmr: an open source python package for analyzing [<sup>15</sup>N, <sup>1</sup>H]-TRACT experiments.

Journal of biomolecular NMR·2026
Same journal

RelCalc: symbolic evaluation of BWR theory relaxation rates in python, applications to TROSY effects in AX[Formula: see text] spin systems.

Journal of biomolecular NMR·2026
Same journal

Solution NMR study of the titin I-band IgI domain I82 shows unusual conformational dynamics.

Journal of biomolecular NMR·2026
Same journal

Methyl-specific NMR of therapeutic antibodies: cost-effective isotopic labeling strategies in CHO cells for high-resolution structural characterization.

Journal of biomolecular NMR·2026
Same journal

AMIGO - Guided assignment of <sup>13</sup>C-methyl labelled proteins.

Journal of biomolecular NMR·2026
Same journal

Super-Resolution solid-state NMR Spectroscopy.

Journal of biomolecular NMR·2026
See all related articles

NMRPipe is a flexible UNIX software environment for processing, analyzing, and visualizing multidimensional NMR data. Its pipeline architecture enhances processing speeds and simplifies complex NMR data analysis for researchers.

Area of Science:

  • Chemistry
  • Biochemistry
  • Structural Biology

Background:

  • Multidimensional Nuclear Magnetic Resonance (NMR) spectroscopy is crucial for determining molecular structures and dynamics.
  • Efficient processing and analysis of complex NMR datasets are essential for routine and research applications.
  • Existing NMR data processing methods often lack flexibility and can be computationally intensive.

Purpose of the Study:

  • To introduce the NMRPipe system, a comprehensive software environment for NMR data processing and analysis.
  • To highlight the advantages of a UNIX-based, pipeline architecture for NMR data handling.
  • To provide a flexible and efficient tool for current and future NMR research demands.

Main Methods:

  • Development of NMRPipe as a UNIX software environment utilizing UNIX pipes for data stream exchange.

Related Experiment Videos

  • Implementation of processing modules for tasks like Fourier transformation and linear prediction.
  • Construction of complete processing schemes using simple UNIX shell scripts.

    • Main Results:

    • NMRPipe enables asynchronous pipeline processing, allowing simultaneous program execution and data flow.
    • The system automatically manages data sizes and calibration information, simplifying scheme construction.
    • Achieved benefits include high flexibility, favorable processing speeds, and efficient resource utilization.

    Conclusions:

    • NMRPipe offers a robust and adaptable solution for multidimensional NMR data processing.
    • The system's design facilitates easier software development, maintenance, and distributed computing.
    • NMRPipe supports both in-memory and disk-bound processing, accommodating various data sizes and formats.