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Updated: Aug 12, 2026

Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology
Published on: May 15, 2012
Synthetic peptides in biochemical research
D C Hancock1, N J O'Reilly, G I Evan
1Biochemistry of the Cell Nucleus and Peptide Synthesis Laboratories, Imperial Cancer Research Fund, London, UK.
Abstract:
Synthetic peptides play an important role in many areas of biological research. Advances in synthetic chemistry and automation over the past few years have resulted in increasingly reliable and rapid syntheses. As a result, peptides are now frequently employed in immunological studies, structural studies, as enzyme substrates, in ligand/receptor studies, and as probes for a range of molecular interactions. This review describes solid-phase peptide synthesis and the applications of synthetic peptides in molecular biology and biochemistry.
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