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Related Experiment Videos

[Clinical effectiveness of Marvelon]

L Marianowski1, B Grzechocińska

  • 1I Katedry i Kliniki Połoznictwa i Ginekologii AM w Warszawie.

Ginekologia Polska
|May 1, 1995
PubMed
Summary

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This study shows Marvelon, a new oral contraceptive, is well-tolerated with minimal side effects. It offers excellent contraceptive efficacy and favorable lipid profile changes in women.

Area of Science:

  • Reproductive Medicine
  • Endocrinology
  • Pharmacology

Background:

  • Oral contraceptives are widely used for family planning.
  • Assessing the safety and efficacy of new formulations is crucial.
  • Marvelon is a novel oral contraceptive agent.

Purpose of the Study:

  • To evaluate the clinical results of Marvelon.
  • To assess its tolerability, side effects, and impact on menstrual cycles.
  • To investigate its effects on body weight, blood pressure, and lipid profiles.

Main Methods:

  • A clinical study involving 32 women over at least 6 cycles.
  • Monitoring of subjective side effects, cycle regularity, and bleeding patterns.
  • Measurement of body weight, blood pressure, and lipid profiles (HDL-Cholesterol, LDL-Cholesterol).
Keywords:
BiologyCholesterolClinical ResearchClinical TrialsContraceptionContraceptive Agents, Female--side effectsContraceptive Agents, Progestin--side effectsContraceptive Agents--side effectsContraceptive EffectivenessContraceptive Methods--side effectsDesogestrel--side effectsDeveloped CountriesEastern EuropeEuropeFamily PlanningGestodene--side effectsLipid Metabolic EffectsLipidsNorgestimate--side effectsOral Contraceptives, Combined--side effectsOral Contraceptives, Low-dose--side effectsOral Contraceptives--side effectsPhysiologyPolandResearch Methodology

Related Experiment Videos

  • Calculation of the Pearl Index for contraceptive efficacy.

    • Main Results:

    • Marvelon demonstrated good tolerability with very low subjective side effects.
    • Menstrual cycles remained regular, with withdrawal bleeding lasting 3-5 days.
    • No significant changes in body weight or blood pressure were observed.
    • A favorable lipid profile was noted, with increased HDL-Cholesterol and decreased LDL-Cholesterol.
    • The Pearl Index was 0.0, indicating high contraceptive effectiveness.

    Conclusions:

    • Marvelon is a well-tolerated and effective oral contraceptive.
    • It offers benefits such as regular cycles, mild bleeding, and a positive impact on lipid profiles.
    • The contraceptive efficacy of Marvelon is very high.