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Paget's sarcoma of the mandible
L L Gleich1, R C Eberle, A R Shaha
1Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati Medical Center, OH 45267-0528, USA.
Head & Neck
|September 1, 1995
Summary
Paget's sarcoma of the mandible is a rare, aggressive cancer in elderly patients. This deadly tumor has a worse prognosis than mandibular osteosarcoma, necessitating early detection and multimodal treatment.
Area of Science:
- Oncology
- Skeletal Pathology
- Surgical Oncology
Background:
- Paget's sarcoma is a rare malignant transformation of Paget's disease, occurring in less than 1% of cases.
- Mandibular involvement is exceptionally rare, with only 9 reported cases, all uniformly fatal.
- This study compares Paget's sarcoma of the mandible to osteosarcoma in similar and different anatomical locations.