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Renal transplantation one week after conception

B W Miller1, T K Howard, J A Goss

  • 1Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Transplantation
|December 15, 1995
PubMed
Summary
This summary is machine-generated.

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Renal transplant recipients can achieve successful pregnancies with good outcomes for both mother and child. This case highlights the safety of immunosuppression and managing infections during pregnancy post-transplant.

Area of Science:

  • Nephrology
  • Immunology
  • Obstetrics

Background:

  • Pregnancy in renal transplant recipients presents unique challenges due to immunosuppression and potential complications.
  • Maintaining graft function and ensuring fetal well-being are primary concerns.

Observation:

  • A renal transplant patient conceived approximately one week post-transplantation.
  • The pregnancy progressed to 38 weeks with the patient receiving quadruple immunosuppression and ganciclovir for cytomegalovirus infection.
  • Routine post-transplantation care was administered throughout the pregnancy and postpartum period.

Findings:

  • The pregnancy resulted in a healthy mother and child, with no decline in maternal renal function.
  • Both mother and child remained healthy at 18 months postpartum.

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  • No adverse effects on the child were observed during gestation or up to 18 months of age.
  • Implications:

    • Renal transplant patients can successfully carry pregnancies to term while maintaining graft function.
    • Aggressive immunosuppression and management of infections like cytomegalovirus are feasible and safe during pregnancy in this population.
    • This case supports the possibility of favorable pregnancy outcomes in renal transplant recipients, even with complex medical management.